The Effects of Ionic Conductances on the Dynamics of Neuronal Activity
Neurological systems have been intriguing humans from the beginnings of civilization thousands of years ago up to this date with so many still unanswered questions. In this presentation we discuss landmark discoveries in and contributions to neuroscience. Such discoveries enabled not only precise experimental measurements and imaging of neuronal activity, but also the development of mathematical models. As a result, we have witnessed remarkable progress over the past few years in the understanding of neurological functions and disorders. Following this discussion, we focus on computational results of a single neuron Hodgkin-Huxley model to study the effects of ionic channel conductances on the neuronal firing rate. Specifically, we will test the individual and combined effects of tuning sodium, potassium, and leak channel parameters.
Mobille, Zach, "The Effects of Ionic Conductances on the Dynamics of Neuronal Activity" (2018). University Research Symposium. 103.