"Investigation of the Mechanism of Magnetosensation in C. elegans" by Aalimah Akinosho

Graduation Term

2025

Degree Name

Master of Science (MS)

Department

School of Biological Sciences

Committee Chair

Andres Vidal-Gadea

Committee Member

Wolfgang Stein

Committee Member

Rosa Epaminondas

Abstract

Organisms interact with abiotic factors like temperature, light, and magnetic fields, shaping their behavior and adaptation. While Earth's magnetic field aids navigation in various species, the molecular mechanisms of magnetosensation remain unclear. This study uses Caenorhabditis elegans to investigate magnetosensation, leveraging its genetic tractability and rapid lifecycle. We identify key molecular components involved in magnetic field detection and assess their roles. Additionally, we explore the effects of reduced magnetic fields, simulating Martian conditions, on biological functions.

Beyond magnetosensation, we examine transgenerational adaptation by studying inherited pathogen avoidance behavior in C. elegans. By investigating how environmental experiences influence progeny, we aim to uncover epigenetic mechanisms of adaptation. This research enhances our understanding of sensory biology, environmental adaptation, and potential challenges for life in space.

KEYWORDS: Magnetosensation, Caenorhabditis elegans, magnetic field detection, transgenerational adaptation, epigenetics, sensory biology, Martian conditions, environmental stress, pathogen avoidance, neural mechanisms

Access Type

Thesis-Open Access

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