Faculty Publications from 2023
Experiencing Short Heat Waves Early in Development Changes Thermal Responsiveness of Turtle Embryos to Later Heat Waves, Anthony Breitenbach, Rosario A. Marroquín-Flores, Ryan T. Paitz, and Rachel M. Bowden
Not all cities are the same: variation in animal phenotypes across cities within urban ecology studies, Javier delBarco-Trillo and Breanna J. Putman
Asynchronous student engagement in analysis of climate data achieves learning objectives related to climate change understanding, statistical competence, and climate anxiety, Thomas Meixner, B. Ciancarelli, E. P. Farrell, D. Silva Garcia, T. Josek, M. M. Kelly, Paul Antone Meister, D. Soule, and Rebekka Darner
Faculty Publications from 2021
Dataset for Response of the Invasive Alliaria Petiolata to Extreme Temperatures and Drought, Roger C. Anderson, Rebecca Anderson, Jonathan T. Bauer, Christopher Loebach, Alicia Mullarkey, and Megan Engelhardt
Mutational Analysis Reveals Potential Phosphorylation Sites in Eukaryotic Elongation Factor 1A That are Important for its Activity, Maria K. Mateyak, Dongming He, Pragati Sharma, and Terri Goss Kinzy
Asp56 in Actin is Critical for the Full Activity of the Amino Acid Starvation-Responsive Kinase Gcn2, Rashmi Ramesh, Martina Dautel, Yongook Lee, Yeonsoo Kim, Kirsty Storey, Susanne Gottfried, Terri Goss Kinzy, Won-Ki Huh, and Evelyn Sattlegger
Faculty Publications from 2019
Microplastic prevalence in two fish species in two U.S. reservoirs, William Perry, Catherine M. O'Reilly, and Raven Hurt
Identifying Dopamine Receptor Genes and Transcription Marbled Crayfish, Wolfgang Stein and Saisupritha Talasu
Faculty Publications from 2018
Demonstration of Translation Elongation Factor 3 Activity From a Non-Fungal Species, Phytophthora infestans, Maria K. Mateyak, Justyna K. Pupek, Alexandra E. Garino, McCllelan C. Knapp, Sarah F. Colmer, Terri Goss Kinzy, and Stephen Dunaway
Faculty Publications from 2017
Breaking the Silos of Protein Synthesis, Maria K. Mateyak and Terri Goss Kinzy
Faculty Publications from 2016
Mechanism and Regulation of Protein Synthesis in Saccharomyces Cerevisiae, Thomas E. Dever, Terri Goss Kinzy, and Graham D. Pavitt
The Unique Evolutionary Distribution of Eukaryotic Elongation Factor 3, Maria Mateyak, Arjun N. Sasikumar, Stephen Dunaway, and Terri Goss Kinzy
Faculty Publications from 2014
In Vivo [35 S]-Methionine Incorporation, Anthony M. Esposito and Terri Goss Kinzy
Methylation of Translation Elongation Factor 1A by the METTL10-Like See1 Methyltransferase Facilitates Tombusvirus Replication in Yeast and Plants, Zhenghe Li, Paulina Alatriste Gonzalez, Zsuzsanna Sasvari, Terri Goss Kinzy, and Peter D. Nagy
Translation Elongation Factor 1A Mutants with Altered Actin Bundling Activity Show Reduced Aminoacyl-tRNA Binding and Alter Initiation via eIF2α Phosphorylation, Winder B. Perez and Terri Goss Kinzy
Mutations in the Chromodomain-like Insertion of Translation Elongation Factor 3 Compromise Protein Synthesis Through Reduced ATPase Activity, Arjun N. Sasikumar and Terri Goss Kinzy
An in vivo Assay for Simultaneous Monitoring of Neuronal Activity and Behavioral Output in the Stomatogastric Nervous System of Decapod Crustaceans, Wolfgang Stein and Florian Diehl
Faculty Publications from 2013
Linezolid Exerts Greater Bacterial Clearance but No Modification of Host Lung Gene Expression Profiling: A Mouse MRSA Pneumonia Model, Jiwang Chen, Gang Feng, Yang Song, Juliane B. Wardenburg, Simon Lin, Ichiro Inoshima, Michael Otto, and Richard G. Wunderink
Amphetamine Elicits Opposing Actions on Readily Releasable and Reserve Pools for Dopamine, Dan P. Covey, Steven A. Juliano, and Paul A. Garris
Deletion of the TPM1 and MDM20 Genes Affect the Mechanical and Structural Properties of Yeast Cells, Annette Doyle, Steven R. Crosby, David R. Burton, Francis Lilley, Gary Johnston, Winder B. Perez, Terri Goss Kinzy, and Mark F. Murphy
ADP-ribosylation of Translation Elongation Factor 2 by Diphtheria Toxin in Yeast Inhibits Translation and Cell Separation, Maria K. Mateyak and Terri Goss Kinzy
Additional Routes to Staphylococcus aureus Daptomycin Resistance as Revealed by Comparative Genome Sequencing, Transcriptional Profiling, and Phenotypic Studies, Yang Song, Aileen Rubio, Radheshyam K. Jayaswal, Jared A. Silverman, and Brian J. Wilkinson
Faculty Publications from 2012
abd-A Regulation by the iab-8 Noncoding RNA, Maheshwar Gummalla, Robert K. Maeda, Javier J. Castro Alvarez, Henrik Gyurkovics, Kevin A. Edwards, Swetha Singari, and Welcome Bender
Seasonal Photoperiods Alter Developmental Time and Mass of an Invasive Mosquito, Aedes albopictus (Diptera: Culicidae), Across Its North-South Range in the United States, Steven A. Juliano, Donald A. Yee, and Steven M. Vamosi
Competitive Abilities in Experimental Microcosms Are Accurately Predicted by a Demographic Index for R*, Ebony G. Murrell and Steven A. Juliano
The Many Roles of the Eukaryotic Elongation Factor 1 Complex, Arjun N. Sasikumar, Winder B. Perez, and Terri Goss Kinzy
Wing Shape as an Indicator of Larval Rearing Conditions for Aedes albopictus and Aedes aegypti (Diptera: Culicidae), C R. Stephens and Steven A. Juliano
Faculty Publications from 2011
Characterization of the Phytochelatin Synthase of Schistosoma mansoni, Debalina Ray and David L. Williams
Synergistic Roles of Eukaryotic Translation Elongation Factors 1Bγ and 1A in Stimulation of Tombusvirus Minus-Strand Synthesis, Zsuzsanna Sasvari, Lara Izotova, Terri Goss Kinzy, and Peter D. Nagy
Evidence That Eukaryotic Translation Elongation Factor 1A (eEF1A) Binds the Gcn2 Protein C Terminus and Inhibits Gcn2 Activity, Jyothsna Visweswaraiah, Sebastien Lageix, Beatriz A. Castilho, Lara Izotova, Terri Goss Kinzy, Alan G. Hinnebusch, and Evelyn Sattlegger
Faculty Publications from 2010
Histone H2A and H2B Are Monoubiquitinated at AID-Targeted Loci, Glen M. Borchert, Nathaniel W. Holton, Kevin A. Edwards, Laura A. Vogel, and Erik D. Larson
The Eukaryotic Translation Elongation Factor 1Bγ Has a Non-guanine Nucleotide Exchange Factor Role in Protein Metabolism, Anthony M. Esposito and Terri Goss Kinzy
Eukaryotic Polyribosome Profile Analysis, Anthony M. Esposito, Maria Mateyak, Dongming He, Marcus Lewis, Arjun N. Sasikumar, Jenna Hutton, Paul R. Copeland, and Terri Goss Kinzy
Drosophila Translational Elongation Factor-1γ Is Modified in Response to DOA Kinase Activity and Is Essential for Cellular Viability, Yujie Fan, Michael Schlierf, Ana Cuervo Gaspar, Catherine Dreux, Arlette Kpebe, Linda Chaney, Aurelie Mathieu, Christophe Hitte, Oliver Gremy, Emiline Sarot, Mark Horn, Yunlong Zhao, Terri Goss Kinzy, and Leonard Rabinow
Targeting of eEF1A With Amaryllidaceae Isocarbostyrils as a Strategy to Combat Melanomas, Gwendoline Van Goietsenoven, Jenna Hutton, Jean-Paul Becker, Benjamin Lallemand, Francis Robert, Florence Lefranc, Christine Pirker, Guy Vandenbussche, Pierre Van Antwerpen, Antonio Evidente, Walter Berger, Martine Prevost, Jerry Pelletier, Robert Kiss, Terri Goss Kinzy, Alexander Kornienko, and Veronique Mathieu
Translation Elongation Factor 1A Facilitates the Assembly of the Tombusvirus Replicase and Stimulates Minus-Strand Synthesis, Zhenghe Li, Judit Pogany, Steven Tupman, Anthony M. Esposito, Terri Goss Kinzy, and Peter D. Nagy
eEF1A: Thinking Outside the Ribosome, Maria K. Mateyak and Terri Goss Kinzy
The Scale of Population Structure in Arabidopsis thaliana, Alexander Platt, Matthew Horton, Yu S. Huang, Yan Li, Alison E. Anastasio, Ni Wayan Mulyati, Jon Agren, Oliver Bossdorf, Diane Byers, Kathleen Donohue, Megan Dunning, Eric B. Holub, Andrew Hudson, Valerie Le Corre, Olivier Loudet, Fabrice Roux, Norman Warthmann, Detlef Weigel, Luz Rivero, Randy Scholl, Magnus Nordborg, Joy Bergelson, and Justin O. Borevitz
Environmental Correlates of Abundances of Mosquito Species and Stages in Discarded Vehicle Tires, Donald A. Yee, Jamie M. Kneitel, and Steven A. Juliano
Faculty Publications from 2009
Expanding the Ribosomal Universe, Jonathan D. Dinman and Terri Goss Kinzy
No Evolutionary Response to Four Generations of Laboratory Selection on Antipredator Behavior of Aedes albopictus: Potential Implications for Biotic Resistance to Invasion, Banugopan Kesavaraju and Steven A. Juliano
Translation Elongation Factor 1A is a Component of the Tombusvirus Replicase Complex and Affects the Stability of the P33 Replication Co-Factor, Zhenghe Li, Judit Pogany, Tadas Panavas, Kai Xu, Anthony M. Esposito, Terri Goss Kinzy, and Peter D. Nagy
Coordination of Eukaryotic Translation Elongation Factor 1A (eEF1A) Function in Actin Organization and Translation Elongation by the Guanine Nucleotide Exchange Factor eEF1Bα, Yvette R. Pittman, Kimberly Kandl, Marcus Lewis, Louis Valente, and Terri Goss Kinzy
Faculty Publications from 2008
Genome-Wide Screen of Saccharomyces Cerevisiae Null Allele Strains Identifies Genes Involved in Selenomethionine Resistance, Jessica Bockhorn, Bharvi Balar, Dongming He, Eden Seitomer, Paul R. Copeland, and Terri Goss Kinzy
A Birth-to-Death View of MRNA From the RNA Recognition Motif Perspective, Terri Goss Kinzy, Lauren A. De Stefano, Anthony M. Esposito, Jennifer M. Hurley, Rohini Roy, Anibal J. Valentin-Acevedo, Kai-Hsiung Chang, Jonathan Davila, Jennifer M. Defren, Jesse Donovan, Patricia Irizarry-Barreto, Anibal Soto, Riza M. Ysla, Liesel Copeland, and Paul R. Copeland
Medical Student Research Exposure Via a Series of Modular Research Programs, Christopher G. Langhammer, Karan Garg, Judith A. Neubauer, Susan Rosenthal, and Terri Goss Kinzy
Geographic variation in adult survival and reproductive tactics of the mosquito Aedes albopictus, Paul T. Leisnham, L M. Sala, and Steven A. Juliano
Detritus type alters the outcome of interspecific competition between Aedes aegypti and Aedes albopictus (Diptera : Culicidae), Ebony G. Murrell and Steven A. Juliano
Guanine Nucleotide Exchange Factor Independence of the G-protein eEF1A Through Novel Mutant Forms and Biochemical Properties, Sedide B. Ozturk and Terri Goss Kinzy
Analysis of Saccharomyces cerevisiae Null Allele Strains Identifies a Larger Role for DNA Damage Versus Oxidative Stress Pathways in Growth Inhibition by Selenium, Eden Seitomer, Bharvi Balar, Dongming He, Paul R. Copeland, and Terri Goss Kinzy
Quantitative High-Throughput Screen Identifies Inhibitors of the Schistosoma mansoni Redox Cascade, Anton Simeonov, Ajit Jadhav, Ahmed A. Sayed, Yuhong Wang, Michael E. Nelson, Craig J. Thomas, James Inglese, David L. Williams, and Christopher P. Austin
Gamendazole, an Orally Active Indazole Carboxylic Acid Male Contraceptive Agent, Targets HSP90AB1 (HSP90BETA) and EEF1A1 (eEF1A), and Stimulates Il1a Transcription in Rat Sertoli Cells, Joseph S. Tash, Ramappa Chakrasali, Sudhakar R. Jakkaraj, Jennifer Hughes, S. Kendall Smith, Kaori Hornbaker, Leslie L. Heckert, Sedide B. Ozturk, M. Kyle Hadden, Terri Goss Kinzy, Brian S.J. Blagg, and Gunda I. Georg
Faculty Publications from 2007
Interspecific and intraspecific differences in foraging preferences of container-dwelling mosquitoes, Kesavaraju Banugopan, Donald A. Yee, and Steven A. Juliano
Characterization of Genetic Alteration Patterns in Human Esophageal Squamous cell Carcinoma Using Selected Microsatellite Markers Spanning Multiple Loci, Yuyang Christine Cai, Chi K. So, Alex Yan Nie, Yunlong Song, Guang-Yu Yang, Li-Dong Wang, Xin Zhao, Terri Goss Kinzy, and Chung S. Yang
A Database of Wing Diversity in the Hawaiian Drosophila, Kevin A. Edwards, Linden T. Doescher, Kenneth Y. Kaneshiro, and Daisuke Yamamoto
Roles of the Negatively Charged N-Terminal Extension of Saccharomyces cerevisiae Ribosomal Protein S5 Revealed by Characterization of a Yeast Strain Containing Human Ribosomal Protein S5, Oleksandr Galkin, Amber A. Bentley, Sujatha Gupta, Beth-Ann Compton, Barsanjit Mazumder, Terri Goss Kinzy, William C. Merrick, Maria Hatzoglou, Tatyana V. Pestova, Christopher U.T. Hellen, and Anton A. Komar
Kinetics of the Interactions between Yeast Elongation Factors 1A and 1Bα, Guanine Nucleotides, and Aminoacyl-tRNA, Kirill B. Gromadski, Tobias Schümmer, Anne Str⌀mgaard, Charlotte R. Knudsen, Terri Goss Kinzy, and Marina V. Rodnina
Improper Organization of the Actin Cytoskeleton Affects Protein Synthesis at Initiation, Stephane R. Gross and Terri Goss Kinzy
Synchronicity: Policing Multiple Aspects of Gene Expression by Ctk1, Michael Hampsey and Terri Goss Kinzy
Thioredoxin glutathione reductase from schistosoma mansoni: An essential parasite enzyme and a key drug target, Angela N. Kuntz, Elizabeth Davioud-Charvet, Ahmed A. Sayed, Lindsay L. Califf, Jean Dessolin, Elias S.J. Arner, and David L. Williams
Taxonomy of the species of Amphigerontia (Psocoptera : Psocidae) of the Rocky Mountains of the United States and Canada, Edward L. Mockford and Johannes E. Anonby
Taxonomy of the species of Amphigerontia (Psocoptera : Psocidae) of the Rocky Mountains of the United States and Canada, Edward L. Mockford and Johannes E. Anonby
Differentiating Between Near- and Non-Cognate Codons in Saccharomyces cerevisiae, Ewan P. Plant, Phuc Nguyen, Jonathan R. Russ, Yvette R. Pittman, Thai Nguyen, Jack T. Quesinberry, Terri Goss Kinzy, and Jonathan D. Dinman
Structure and Function of the Eukaryotic Ribosome and Elongation Factors, Derek J. Taylor, Joachim Frank, and Terri Goss Kinzy
Direct and indirect effects of animal detritus on growth, survival, and mass of invasive container mosquito Aedes albopictus (Diptera : Culicidae, Donald A. Yee, Banugopan Kesavaraju, and Steven A. Juliano
Faculty Publications from 2006
Domain and Nucleotide Dependence of the Interaction Between Saccharomyces cerevisiae Translation Elongation Factors 3 and 1A, Monika Anand, Bharvi Balar, Rory Ulloque, Stephane R. Gross, and Terri Goss Kinzy
Structure of eEF3 and the Mechanism of Transfer RNA Release From the E-Site, Christian B. F. Andersen, Thomas Becker, Michael Blau, Monika Anand, Mario Halic, Bharvi Balar, Thorsten Mielke, Thomas Boesen, Jan Skov Pedersen, Christian M. T. Spahn, Terri Goss Kinzy, Gregers Rom Andersen, and Roland Beckmann
Rapid Depletion of Mutant Eukaryotic Initiation Factor 5A at Restrictive Temperature Reveals Connections to Actin Cytoskeleton and Cell Cycle Progression, Ishita Chatterjee, Stephane R. Gross, Terri Goss Kinzy, and Kuang Yu Chen
Translation Elongation Factor 2 Anticodon Mimicry Domain Mutants Affect Fidelity and Diphtheria Toxin Resistance, Pedro A. Ortiz, Rory Ulloque, George K. Kihara, Haiyan Zheng, and Terri Goss Kinzy
Unique Classes of Mutations in the Saccharomyces cerevisiae G-Protein Translation Elongation Factor 1A Suppress the Requirement for Guanine Nucleotide Exchange, Sedide B. Ozturk, Melanie R. Vishnu, Olubunmi Olarewaju, Lea M. Starita, Daniel C. Masison, and Terri Goss Kinzy
Mg2+ and a Key Lysine Modulate Exchange Activity of Eukaryotic Translation Elongation Factor 1Bα, Yvette R. Pittman, Louis Valente, Mads Gravers Jeppesen, Gregers Rom Andersen, Smita Patel, and Terri Goss Kinzy
Faculty Publications from 2005
Proteasome-Mediated Degradation of Cotranslationally Damaged Proteins Involves Translation Elongation Factor 1A, Show-Mei Chuang, Li Chen, David Lambertson, Monika Anand, Terri Goss Kinzy, and Kiran Madura
Development and Evaluation of a Peer-Tutoring Program for Graduate Students, H. Liesel Copeland and Terri Goss Kinzy
Asymmetrical competition and patterns of abundance of Aedes albopictus and Culex pipiens (Diptera : Culicidae), Katie S. Costanzo, Kimberly Mormann, and Steven A. Juliano
Translation Elongation Factor 1A is Essential for Regulation of the Actin Cytoskeleton and Cell Morphology, Stephane R. Gross and Terri Goss Kinzy
Novel Characteristics of the Biological Properties of the Yeast Saccharomyces cerevisiae Eukaryotic Initiation Factor 2A, Anton A. Komar, Stephane R. Gross, Diane Barth-Baus, Ryan Strachan, Jack O. Hensold, Terri Goss Kinzy, and William C. Merrick
Interplay Between GCN2 and GCN4 Expression, Translation Elongation Factor 1 Mutations and Translational Fidelity in Yeast, Tanya Magazinnik, Monika Anand, Evelyn Sattlegger, Alan G. Hinnebusch, and Terri Goss Kinzy
Dominant-Negative Mutant Phenotypes and the Regulation of Translation Elongation Factor 2 Levels in Yeast, Pedro A. Ortiz and Terri Goss Kinzy
Faculty Publications from 2004
Purification and Crystallization of the Yeast Translation Elongation Factor eEF3, Christian Folstead Anderson, Monika Anand, Thomas Boesen, Lan Bich Van, Terri Goss Kinzy, and Gregers Rom Andersen
The Translation Elongation Factor eEF1B Plays a Role in the Oxidative Stress Response Pathway, Olubunmi Olarewaju, Pedro A. Ortiz, Wasimul Q. Chowdhury, Ishita Chatterjee, and Terri Goss Kinzy
Faculty Publications from 2003
Functional Interactions Between Yeast Translation Eukaryotic Elongation Factor (eEF) 1A and eEF3, Monika Anand, Kalpana Chakraburtty, Matthew J. Marton, Alan G. Hinnebusch, and Terri Goss Kinzy
Identification and Characterization of an Inhibitor of Eukaryotic Elongation Factor 2 Kinase Against Human Cancer Cell Lines, Sonia Arora, Jin-Ming Yang, Terri Goss Kinzy, Ryutaro Utsumi, Tadashi Okamoto, Takashi Kitayama, Pedro A. Ortiz, and William N. Hait
Convergent habitat segregation of Aedes aegypti and Aedes albopictus (Diptera : Culicidae) in southeastern Brazil and Florida, Marieta A H Braks, Ricardo Lourenco-De-Oliveira, Steven A. Juliano, Nildimar A. Honorio, and L Philip Lounibos
Divergent tRNA-Like Element Supports Initiation, Elongation, and Termination of Protein Biosynthesis, Eric Jan, Terri Goss Kinzy, and Peter Sarnow
The Crystal Structure of the Glutathione S-Transferase-like Domain of Elongation Factor 1Bγ from Saccharomyces Cerevisiae, Mads Gravers Jeppesen, Pedro A. Ortiz, William Shepard, Terri Goss Kinzy, Jens Nyborg, and Gregers Rom Andersen
Two Crystal Structures Demonstrate Large Conformational Changes in the Eukaryotic Ribosomal Translocase, Rene Jorgensen, Pedro A. Ortiz, Anne Carr-Schmid, Poul Nissen, Terri Goss Kinzy, and Gregers Rom Andersen
Mutation of a Conserved CDK Site Converts a Metazoan Elongation Factor 1Bβ Subunit into a Replacement for Yeast eEF1Bα, Joseph R. Pomerening, Louis Valente, Terri Goss Kinzy, and Thomas W. Jacobs
Yeast as a Sensor of Factors Affecting the Accuracy of Protein Synthesis, Louis Valente and Terri Goss Kinzy
Faculty Publications from 2002
Novel G-Protein Complex Whose Requirement Is Linked to the Translational Status of the Cell, Anne Carr-Schmid, Christine Pfund, Elizabeth A. Craig, and Terri Goss Kinzy
Purification and Crystallization of the Yeast Elongation Factor eEF2, Rene Jorgensen, Anne Carr-Schmid, Pedro A. Ortiz, Terri Goss Kinzy, and Gregers Rom Andersen
Identification of a Role for Actin in Translational Fidelity in Yeast, Kimberly Kandl, Raj Munshi, Pedro A. Ortiz, Gregers Rom Andersen, Terri Goss Kinzy, and Alison E. Adams
New Targets for Antivirals: The Ribosomal A-Site and the Factors That Interact With It, Terri Goss Kinzy, Jason W. Harger, Anne Carr-Schmid, Jane Kwon, Mythili Shastry, Michael Justice, and Jonathan D. Dinman
Faculty Publications from 2001
Temperature effects on the dynamics of Aedes albopictus (Diptera : Culicidae) populations in the laboratory, Barry W. Alto and Steven A. Juliano
Precipitation and temperature effects on populations of Aedes albopictus (Diptera : Culicidae): Implications for range expansion, B W. Alto and Steven A. Juliano
Translation Elongation Factor 1 Functions in the Yeast Saccharomyces cerevisiae, Monika Anand, Louis Valente, Anne Carr-Schmid, Raj Munshi, Olubunmi Olarewaju, Pedro A. Ortiz, and Terri Goss Kinzy
Crystal Structures of Nucleotide Exchange Intermediates in the eEF1A–eEF1Bα Complex, Gregers Rom Andersen, Louis Valente, Lise Pedersen, Terri Goss Kinzy, and Jens Nyborg
Overexpression of Translation Elongation Factor 1A Affects the Organization and Function of the Actin Cytoskeleton in Yeast, Raj Munshi, Kimberly A. Kandl, Anne Carr-Schmid, Johanna L. Whitacre, Alison E. M. Adams, and Terri Goss Kinzy
Crystallization of the Yeast Elongation Factor Complex eEF1A-eEF1B Alpha, Lise Pedersen, Gregers Rom Andersen, Charlotte Rohde Knudsen, Terri Goss Kinzy, and Jens Nyborg
Characterization of a General Stabilizer Element That Blocks Deadenylation-Dependent mRNA Decay, Maria J. Ruiz-Echevarria, Raj Munshi, Julie Tomback, Terri Goss Kinzy, and Stuart W. Peltz
Faculty Publications from 2000
Structural Basis for Nucleotide Exchange and Competition with tRNA in the Yeast Elongation Factor Complex eEF1A:eEF1Bα, Gregers Rom Andersen, Lise Pederson, Louis Valente, Ishita Chatterjee, Terri Goss Kinzy, Morten Kjeldgaard, and Jens Nyborg