DOI
10.30707/1764607194.332424
Document Type
Senior Thesis
Publication Date
Spring 2025
Committee Chair
Thomas Hammond
Committee Member
Kevin Edwards
Abstract
Neurospora crassa is a genus of fungus that exhibits a phenomenon called Sk-3 spore killing. Sk-3 spore killing occurs when an Sk-3 killer strain mates with an Sk-3 sensitive strain, and it results in the death of half of the offspring. A DNA interval called i350, located on N. crassa Chromosome III, has previously been identified as critical for spore killing. Here, to obtain a more detailed understanding of this DNA interval, the effects of the deletion of related DNA intervals i386 and i408 on spore killing has been studied. Deletion of i386 resulted in no disruption of spore killing while deletion of i408 disrupted spore killing. These results provide a better understanding of the DNA sequences required for the spore killing process.
Funding Source
This work was supported by the National Science Foundation (Award Number 200595, Elucidating the mechanism of meiotic drive by mRNA editing-mediated spore killing in Neurospora fungi).
Recommended Citation
Damkoehler, Kole, "Determining the Effects that Deletion of i386 and i408 have on Sk-3-Type Spore Killing" (2025). Senior Theses – Biological Sciences. 10.
https://ir.library.illinoisstate.edu/stbs/10